5 Oyster Mushroom Benefits + How To Use Them

Pierre Van Zylhealth

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Flush of pearl oyster mushrooms growing on kitchen counter

When we talk about the health benefits of mushrooms, exotic species like lion’s manechaga and reishi often take the spotlight, but did you know that one of the easiest mushroom species to grow (and prepare) also contains therapeutic properties? 

It’s true, oyster mushrooms are both delicious AND beneficial for evening skin tone, de-stressing, supporting immune function and more. 

We’ll cover the benefits in just a minute, but first I want to mention that none of these statements have been evaluated by the FDA, this article is not medical advice, and it is not meant to diagnose or treat any condition. Please talk with your healthcare provider about any dietary supplements you are considering. 

Now that we’ve got that out of the way, let’s dive in!

What are oyster mushrooms?

For starters, they’re edible mushrooms that get their name from the shell-like appearance of their fruiting bodies – the part we typically think of as mushrooms – not their flavor. Also known as tree oysters and hiratake, which means “flat mushroom” in Japanese, they grow in beautiful clusters and have delicate gills on the underside of the caps. 

The variety you typically see in grocery stores are Pleurotus ostreatus (pearl oysters), but there are several other varieties that are both delicious and easy to grow, including: 

  • Pleurotus citrinopileatus (golden oyster)
  • Pleurotus salmoneostramineus (pink oyster)
  • Pleurotus Columbinus (blue oyster)
  • Pleurotus eryngii (King oyster, or as it was referred to in fourth century China the “mushroom flower of heaven”)

In the wild they grown on hardwood trees, particularly dead wood, but you can easily grow them on your kitchen counter, too. They’re rich in minerals including phosphorus, potassium, copper, iron, magnesium, zinc, manganese, and selenium, plus several important bioactive compounds we’ll cover later in this article. 

oyster mushroom health benefits

5 Benefits of Oyster Mushrooms

“These are among the best edibles, with high protein content (some species have up to 35 percent protein), high digestibility, high fiber, high mineral content, and 15 to 20 percent beta-glucans.” – Christopher Hobbs’s Medicinal Mushrooms

1. Helps “Melt Away The Stress of The Workday”

According to Tero Isokauppaila, author of Healing Mushrooms and founder of Four Sigmatic, oyster mushrooms are rich in B vitamins, particularly B6 which: 

works wonders to calm the body and boost spirits (B6 stimulates the body to produce serotonin, a neurotransmitter that regulates our sleep and mood. For this reason, we often like to suggest eating oyster mushrooms in the evening, as its mellowing properties can melt away the stress of the workday instead of a glass of wine (or with it, if it’s been a really tough day).” (1)

2. Supports The Immune System

Oyster mushrooms also contain powerful beta-glucans with tremendous immunomodulating powers” (1)

Our immune cells have several types of receptors that work specifically with polysaccharides created by mushrooms. Oyster mushrooms are rich in beta-glucans, a type of polysaccharide, that works synergistically with the immune system.

“In Medicinal Mushrooms: A Clinical Guide, Martin Powell writes:

Polysaccharides are not the sole category of therapeutically active compound present in mushrooms but they are the most widespread, and, in many but not all mushrooms, the most important with a profound impact in the immune system mediated by a number of fungal polysaccharide-specific receptors on the surface of several classes of immune cell.”

In other words, our cells have receptors that are specifically designed to work with the kinds of polysaccharides generated by mushrooms, leading Power to wonder if they might be “essential nutrients for our immune system.”

In this study, a particular beta-glucan produced by oyster mushrooms (pleuran beta-glucan) had “a positive effect on cellular immunity when given to elite athletes.” (2) (3)

3. Helps Even Skin Tone

According to Tero Isokauppaila, a compound found in oyster mushrooms – kojic acid – can help fade uneven skin tone associated with sun spots and freckles. It can be applied externally via a serum like this one or taken internally.

He recommends taking the following estimated amounts (by weight) for a period of a few weeks to a few months to get the benefit:

  • Dual extraction products – 1.5 grams
  • Hot water extraction products = 3 grams
  • Dried mushrooms – 30 grams
  • Fresh mushrooms – 270 grams (1)

4. Antioxidant Support

Oyster mushrooms contain an amino acid called ergothioneine, which is a unique antioxidant made by fungi. (4)

Antioxidants help counteract excess oxidative stress that can lead to accelerated aging and several disease processes, but some lose their effectiveness when they’re exposed to heat. Fortunately, ergothioneine levels stay the same when mushrooms are cooked (which they need to be as we’ll cover in the safety section below). 

According to this study, oyster mushrooms are also a rich source of other antioxidants including phenolics, flavonoids, ascorbic acid, glycosides, tocopherols, polysaccharides, and carotenoids. 

5. May Support Heart Health

Research suggests that the beta-glucans in oyster mushrooms may support healthy blood pressure levels. (Healing mushrooms) (https://pubmed.ncbi.nlm.nih.gov/2738717/)

Also, according to mycologist and herbalist Christopher Hobbs, “this mushroom contains a closely related molecule to lovastatin, a statin medication prescribed to lower cholesterol in the body.” 

However, he adds that the mushroom molecule is quite mild and the potential benefits are mostly theoretical in humans although a number of animal studies show promise. More research is needed to understand the potential benefits of oyster mushrooms for encouraging healthy cholesterol levels. 

Other Possible Benefits

In “Traditional Chinese Medicine, oyster mushrooms were often used for joint and muscle relaxation.” (Healing Mushrooms)

Polysaccharides such as beta-glucans also: 

  • Support glucose metabolism (https://pubmed.ncbi.nlm.nih.gov/25382404/)
  • Have a prebiotic effect that supports gut health (3)
  • Support autophagy (Taking out the cellular trash)  (4)


Like shiitake and maitake, the oyster mushroom is a veritable culinary delicacy, and has historically been used in Asian cuisines as a meat substitute due to its high levels of protein and meaty texture (though it’s perfectly edible and delicious, this mushroom must be cooked before eating as the heat eliminates a toxic protein it contains).” (1, emphasis mine)

For general wellness benefits, Christopher Hobbs recommends “one or two cooked fruiting bodies two or three times a week, at least.” 

For supporting healthy blood lipid levels and glucose metabolism, he suggests “3 to 4 grams of the dried and powdered fruiting bodies, or about 800 mg of a dried tea extract. This would amount to 1/2 to 1 teaspoon.” (2)

How To Use Oyster Mushrooms

best mushroom kits for beginners

Want To Grow Oyster Mushrooms On Your Kitchen Counter?

It’s easier than you probably think. Here’s how

1. Isokauppila, Tero (2017) Healing Mushrooms

2. Hobbs, Christopher (2021) Christopher Hobbs’s Medicinal Mushrooms: The Essential Guide

3. Bobovčák, Marián et. al. (2010) Effect of Pleuran (β-glucan from Pleurotus ostreatus ) supplementation on cellular immune response after intensive exercise in elite athletes

4. Penn State University (2005) New method shows mushrooms a top source for one antioxidant

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